tert-Butyl 2-bromopropanoate → HCID 67011590, compound

HRID 2240912Notes

Reaction equation

HRID 2240912 reaction equation
[CH:1]1([CH2:4][NH:5][C:6]2[CH:7]=[C:8]([C:14]#[N:15])[C:9]([C:12]#[N:13])=[CH:10][CH:11]=2)[CH2:3][CH2:2]1.Br[CH:17]([CH3:25])[C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19]>>[CH:1]1([CH2:4][N:5]([C:6]2[CH:11]=[CH:10][C:9]([C:12]#[N:13])=[C:8]([C:14]#[N:15])[CH:7]=2)[C@H:17]([C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH3:25])[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 545327tert-Butyl 2-bromopropanoateHCID 57633701HCID 57633701, compound

Product 1

HCID 67011590HCID 67011590, compound

Procedure

Synthesized in a manner similar to example 1B using 4-[(cyclopropylmethyl)amino]-1,2-benzenedicarbonitrile and 1,1-dimethylethyl 2-bromopropanoate: MS (ES) m/z 326 (M+1).

Workup

  1. customSynthesized in a manner similar to example 1B

Sources & evidence

ORD record
ord-d42e4b4181c5458f845426a9265a1990
Source dataset
uspto-grants-2010_05
Patent number
US07723385B2

Reaction notes

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