1-(Difluoromethoxy)-4-iodobenzene → 5-(4-Difluoromethoxy-phenylethynyl)-2-methoxy-benzonitrile

Participants

Reaction Steps

The title compound was prepared in substantially the same manner as described in Example 12, step 3 starting from 1-Difluoromethoxy-4-iodo-benzene (0.17 g, 0.64 mmol), and 5-Ethynyl-2-methoxy-benzonitrile (0.10 g, 0.64 mmol), and was obtained as a light brown solid, (0.170 g, 89%), identified by NMR and mass spectral analyses. MS (APPI+): 299 (M+)

Provenance & Evidence