HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Hydroxymethyl-4-(3-thienyl)-7-hydroxy-2-naphthoic acid → 3-Hydroxymethyl-4-(3-furyl)-7-hydroxy-2-naphthoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Hydroxymethyl-4-(3-thienyl)-7-hydroxy-2-naphthoic acid | HCID 19930245 | — |
| Reactant | 3-Hydroxy-methyl-4-(3-furyl)-7-hydroxy-2-naphthoic acid | HCID 67809950 | — |
| Product | 3-Hydroxymethyl-4-(3-furyl)-7-hydroxy-2-naphthoic acid | HCID 19930226 | — |
| Product | 3-Hydroxy-methyl-4-(3-furyl)-7-hydroxy-2-naphthoic acid | HCID 67809950 | — |
Reaction Steps
Following the procedure described in Example 7, but substituting (1S,5R) 3-[3-(3α-hydroxy-6,8-dioxabicyclo[3.2.1]octanyl)]benzyl alcohol (Alcohol 3) for 5-[4-(4-hydroxy)tetrahydropyranyl]pyridin-3-ylmethanol (Alcohol 1), and substituting 3-hydroxymethyl-4-(3-thienyl)-7-hydroxy-2-naphthoic acid, lactone form (Lactone 4), for 3-hydroxymethyl-4-(3-furyl)-7-hydroxy-2-naphthoic acid, lactone form (Lactone 1), the title compound was obtained as a solid; m.p. 221°-222° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05428060 |
| Source dataset | uspto-grants-1995_06 |
| ORD ID | ord-abe1c194189e4931a9a4594b9c949bc7 |
| Source note | uspto-grants-1995_06 |