HCID 68607819, compound → HCID 58989753, compound

HRID 2241105Notes

Reaction equation

HRID 2241105 reaction equation
[C:1]([C:3]1[C:11]2[CH2:10][CH2:9][NH:8][CH2:7][C:6]=2[S:5][C:4]=1[NH:12][C:13](=[O:25])[CH:14]=[CH:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[O:22][CH2:23][CH3:24])#[N:2].C([C:28]1C2CCNCC=2S[C:29]=1[NH:37][C:38](=[O:46])C=CC1OC=CC=1)#N>>[CH2:29]([NH:37][C:38]([N:8]1[CH2:9][CH2:10][C:11]2[C:3]([C:1]#[N:2])=[C:4]([NH:12][C:13](=[O:25])/[CH:14]=[CH:15]/[C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[O:22][CH2:23][CH3:24])[S:5][C:6]=2[CH2:7]1)=[O:46])[CH3:28]

Participants

3

Reactant 2

HCID 68607819HCID 68607819, compoundHCID 68608547HCID 68608547, compound

Product 1

HCID 58989753HCID 58989753, compound

Procedure

The following compounds 246 to 251 may be prepared according to general procedure FF described later herein starting from N-(3-cyano-4,5,6,7-tetrahydro-thieno[2,3-c]pyridin-2-yl)-3-(2-ethoxy-phenyl)-acrylamide or N-(3-cyano-4,5,6,7-tetrahydro-thieno[2,3-c]pyridin-2-yl)-3-(furan-2-yl)-acrylamide respectively.

Sources & evidence

ORD record
ord-14b628be3dac413cb627edf2b306f34a
Source dataset
uspto-grants-2010_05
Patent number
US07723523B2

Reaction notes

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