反应详情

A mixture of 4-chlorobutyl pentafluorophenyl carbonate (1.69 g, 5.3 mmol) and NaI (7.99 g, 53.3 mmol) in CH3CN (20 ml) was refluxed under nitrogen for 960 minutes. Then the solvent was evaporated and the residue taken up with CH2Cl2 and washed with water (2×50 ml). The organic phase was then dried and evaporated yielding 4-iodobutyl pentafluorophenyl carbonate (1.95 g, 90%) as a yellow oil that was used without further purification.

1. temperaturewas refluxed under nitrogen for 960 minutes
2. customThen the solvent was evaporated
3. washwashed with water (2×50 ml)
4. customThe organic phase was then dried
5. customevaporated