3-Fluorobenzenesulfonyl Chloride → HCID 68406243, compound

HRID 2241128Notes

Reaction equation

HRID 2241128 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([S:8]([NH:11][C:12]2[CH:13]=[C:14]([CH:27]=[CH:28][CH:29]=2)[C:15]([NH:17][C:18]2[CH:26]=[CH:25][C:21]([C:22]([OH:24])=[O:23])=[CH:20][CH:19]=2)=[O:16])(=[O:10])=[O:9])[CH:5]=[CH:6][CH:7]=1.F[C:31]1C=C(S(Cl)(=O)=O)C=C[CH:36]=1>>[CH2:31]([O:23][C:22](=[O:24])[C:21]1[CH:25]=[CH:26][C:18]([NH:17][C:15](=[O:16])[C:14]2[CH:27]=[CH:28][CH:29]=[C:12]([NH:11][S:8]([C:4]3[CH:5]=[CH:6][CH:7]=[C:2]([F:1])[CH:3]=3)(=[O:9])=[O:10])[CH:13]=2)=[CH:19][CH:20]=1)[CH3:36]

Participants

3

Reactant 2

HCID 27342583-Fluorobenzenesulfonyl ChlorideHCID 11979262HCID 11979262, compound

Product 1

HCID 68406243HCID 68406243, compound

Procedure

4-[3-(3-Fluoro-benzenesulfonylamino)-benzoylamino]-benzoic acid, MS (ISP): m/e=413.1 (M−H), was prepared in analogy to example 1, steps A to D. Step C was performed using 3-fluoro-benzensulfonyl chloride and yielded 4-[3-(3-fluoro-benzenesulfonylamino)-benzoylamino]-benzoic acid ethyl ester, which was hydrolyzed in step D.

Sources & evidence

ORD record
ord-14f184433e5d49acbd4980ddc5fd2ad9
Source dataset
uspto-grants-2010_05
Patent number
US07723538B2

Reaction notes

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