2-Naphthalenesulfonyl chloride → HCID 67549455, compound

HRID 2241129Notes

Reaction equation

HRID 2241129 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[S:11]([NH:14][C:15]1[CH:16]=[C:17]([CH:30]=[CH:31][CH:32]=1)[C:18]([NH:20][C:21]1[CH:29]=[CH:28][C:24]([C:25]([OH:27])=[O:26])=[CH:23][CH:22]=1)=[O:19])(=[O:13])=[O:12].[CH:33]1C2C(=CC=CC=2)C=C[C:34]=1S(Cl)(=O)=O>>[CH2:33]([O:26][C:25](=[O:27])[C:24]1[CH:28]=[CH:29][C:21]([NH:20][C:18](=[O:19])[C:17]2[CH:30]=[CH:31][CH:32]=[C:15]([NH:14][S:11]([C:2]3[CH:3]=[CH:4][C:5]4[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=4)[CH:1]=3)(=[O:12])=[O:13])[CH:16]=2)=[CH:22][CH:23]=1)[CH3:34]

Participants

3

Reactant 2

HCID 71252-Naphthalenesulfonyl chlorideHCID 11979263HCID 11979263, compound

Product 1

HCID 67549455HCID 67549455, compound

Procedure

4-[3-(Naphthalene-2-sulfonylamino)-benzoylamino]-benzoic acid, MS (ISP): m/e=445.1 (M−H), was prepared in analogy to example 1, steps A to D. Step C was performed using naphthalene-2-sulfonyl chloride and yielded 4-[3-(naphthalene-2-sulfonylamino)-benzoylamino]-benzoic acid ethyl ester, which was hydrolyzed in step D.

Sources & evidence

ORD record
ord-7efbb3316da44152aeb1d4dc0e97300f
Source dataset
uspto-grants-2010_05
Patent number
US07723538B2

Reaction notes

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