Benzenesulfonyl chloride, 3,4-dichloro- → HCID 68687652, compound

HRID 2241130Notes

Reaction equation

HRID 2241130 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([S:9]([NH:12][C:13]2[CH:14]=[C:15]([CH:28]=[CH:29][CH:30]=2)[C:16]([NH:18][C:19]2[CH:27]=[CH:26][C:22]([C:23]([OH:25])=[O:24])=[CH:21][CH:20]=2)=[O:17])(=[O:11])=[O:10])[CH:5]=[CH:6][C:7]=1[Cl:8].Cl[C:32]1C=C(S(Cl)(=O)=O)C=C[C:37]=1Cl>>[CH2:32]([O:24][C:23](=[O:25])[C:22]1[CH:26]=[CH:27][C:19]([NH:18][C:16](=[O:17])[C:15]2[CH:28]=[CH:29][CH:30]=[C:13]([NH:12][S:9]([C:4]3[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=3)(=[O:10])=[O:11])[CH:14]=2)=[CH:20][CH:21]=1)[CH3:37]

Participants

3

Reactant 2

HCID 7383Benzenesulfonyl chloride, 3,4-dichloro-HCID 11979264HCID 11979264, compound

Product 1

HCID 68687652HCID 68687652, compound

Procedure

4-[3-(3,4-Dichloro-benzenesulfonylamino)-benzoylamino]-benzoic acid, MS (ISP): m/e=462.9 (M−H), was prepared in analogy to example 1, steps A to D. Step C was performed using 3,4-dichloro-benzenesulfonyl chloride and yielded 4-[3-(3,4-dichloro-benzenesulfonylamino)-benzoylamino]-benzoic acid ethyl ester, which was hydrolyzed in step D.

Sources & evidence

ORD record
ord-145672d44113407a88a2832203c13e76
Source dataset
uspto-grants-2010_05
Patent number
US07723538B2

Reaction notes

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