5-(2-(Methylthio)-4-pyrimidinyl)-2-thiophenesulfonyl chloride → HCID 68406438, compound

Participants

Reaction Steps

4-{3-[5-(2-Methylsulfanyl-pyrimidin-4-yl)-thiophene-2-sulfonylamino]-benzoylamino}-benzoic acid, MS (ISP): m/e=525.2 (M−H), was prepared in analogy to example 1, steps A to D. Step C was performed using 5-(2-methylsulfanyl-pyrimidin-4-yl)-thiophene-2-sulfonyl chloride and yielded 4-{3-[5-(2-methylsulfanyl-pyrimidin-4-yl)-thiophene-2-sulfonylamino]-benzoylamino}-benzoic acid ethyl ester, which was hydrolyzed in step D.

Provenance & Evidence