3-Hydroxymethyl-4-(3-thienyl)-7-hydroxy-2-naphthoic acid → 3-Hydroxymethyl-4-(3-furyl)-7-hydroxy-2-naphthoic acid

Participants

Reaction Steps

Following the procedure described in Example 7, but substituting 6-[4-(4-hydroxy)tetrahydropyranyl]pyridin-2-ylmethanol (Alcohol 2) for 5-[4-(4-hydroxy)tetrahydropyzanyl]pyridin-3-ylmethanol (Alcohol 1), and substituting 3-hydroxymethyl-4-(3-thienyl)-7-hydroxy-2-naphthoic acid, lactone form (Lactone 4), for 3-hydroxymethyl-4-(3-furyl)-7-hydroxy-2-naphthoic acid, lactone form (Lactone 1), the title compound was obtained as a solid.

Provenance & Evidence