HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, 1-iodo-4-(trifluoromethyl)- → [5-(4-Isopropyl-piperazine-1-carbonyl)-1-(4-trifluoromethyl-phenyl)-1h-indol-2-yl]-morpholin-4-yl-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, 1-iodo-4-(trifluoromethyl)- | HCID 67993 | — |
| Reactant | [5-(4-Isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-morpholin-4-yl-methanone | HCID 68683056 | — |
| Product | [5-(4-Isopropyl-piperazine-1-carbonyl)-1-(4-trifluoromethyl-phenyl)-1h-indol-2-yl]-morpholin-4-yl-methanone | HCID 68682850 | — |
Reaction Steps
The title compound was synthesized in analogy to example 116, from [5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-morpholin-4-yl-methanone and 4-iodobenzotrifluoride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07723325B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-a77a020050124aa08cda60a5dde80035 |
| Source note | uspto-grants-2010_05 |