5-Bromo-N-methylpyrimidin-2-amine → HCID 24780803, compound

HRID 2241820Notes

Reaction equation

HRID 2241820 reaction equation
[CH3:1][O:2][C:3]1[CH:19]=[CH:18][C:6]2[N:7]=[C:8]([C:10]3[CH:17]=CC(NC)=C[CH:11]=3)[O:9][C:5]=2[CH:4]=1.BrC1C=[N:23][C:24]([NH:27][CH3:28])=[N:25]C=1>>[CH3:1][O:2][C:3]1[CH:19]=[CH:18][C:6]2[N:7]=[C:8]([C:10]3[CH:11]=[N:23][C:24]([NH:27][CH3:28])=[N:25][CH:17]=3)[O:9][C:5]=2[CH:4]=1

Participants

3

Reactant 2

HCID 130981845-Bromo-N-methylpyrimidin-2-amineHCID 68547614HCID 68547614, compound

Product 1

HCID 24780803HCID 24780803, compound

Procedure

The title compound was synthesised according to the procedure described for 4-(6-methoxy-1,3-benzoxazol-2-yl)-N-methylaniline starting from 5-bromo-N-methylpyrimidin-2-amine. 1H NMR δ ppm 8.84-9.02 (m, 2H) 7.95 (d, 1H) 7.61 (d, 1H) 7.37 (d, 1H) 6.97 (dd, 1 H) 3.83 (s, 3H) 2.89 (d, 3H); ES-MS m/z 257 (M+H).

Sources & evidence

ORD record
ord-1ab4a75401a34a8dbd13634582e825f0
Source dataset
uspto-grants-2010_03
Patent number
US07670591B2

Reaction notes

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