HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(Dimethylamino)-5-pyrimidinecarbaldehyde → Methyl 2-[2-(dimethylamino)pyrimidin-5-yl]-1,3-benzoxazole-6-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(Dimethylamino)-5-pyrimidinecarbaldehyde | HCID 795544 | — |
| Edukt | Benzoic acid, 4-amino-3-hydroxy-, methyl ester | HCID 7020619 | — |
| Edukt | 5-(6-Methoxy-1,3-benzoxazol-2-yl)-2-fluoropyridine | HCID 24780956 | — |
| Produkt | Methyl 2-[2-(dimethylamino)pyrimidin-5-yl]-1,3-benzoxazole-6-carboxylate | HCID 24780957 | 72,3% |
Reaktionsschritte
The synthesis was performed according to the procedure described for 5-(6-methoxy-1,3-benzoxazol-2-yl)-2-fluoropyridine starting with 180 mg of 2-dimethylamino-pyrimidine-5-carbaldehyde and 200 mg of methyl 4-amino-3-hydroxybenzoate to give 256.8 mg of the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07670591B2 |
| Quelldatensatz | uspto-grants-2010_03 |
| ORD ID | ord-93f7bbd4bdcc4cb88643808d06832248 |
| Quellennotiz | uspto-grants-2010_03 |