HCID 58154431, compound → HCID 59205151, compound

HRID 2242035Notes

Reaction equation

HRID 2242035 reaction equation
Cl[C:2]1[CH:7]=[CH:6][N:5]=[C:4]([NH:8][C:9]2[CH:14]=[C:13]([O:15][CH3:16])[C:12]([O:17][CH3:18])=[C:11]([O:19][CH3:20])[CH:10]=2)[N:3]=1.[NH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([N:28]([CH3:30])[CH3:29])[C:23]=1[S:31]([NH2:34])(=[O:33])=[O:32]>>[CH3:29][N:28]([CH3:30])[C:24]1[CH:25]=[CH:26][CH:27]=[C:22]([NH:21][C:2]2[CH:7]=[CH:6][N:5]=[C:4]([NH:8][C:9]3[CH:14]=[C:13]([O:15][CH3:16])[C:12]([O:17][CH3:18])=[C:11]([O:19][CH3:20])[CH:10]=3)[N:3]=2)[C:23]=1[S:31]([NH2:34])(=[O:33])=[O:32]

Participants

3

Reactant 2

HCID 58154431HCID 58154431, compoundHCID 66915943HCID 66915943, compound

Product 1

HCID 59205151HCID 59205151, compound

Procedure

2-(Dimethyl-amino)-6-[2-(3,4,5-trimethoxy-phenylamino)-pyrimidin-4-ylamino]-benzenesulfonamide is prepared as described in Example 1 step C by using 4-chloro-pyrimidin-2-yl)-(3,4,5-trimethoxy-phenyl)-amine (example 1 step A) and 2-amino-6-dimethylamino-benzenesulfonamide.

Sources & evidence

ORD record
ord-346afc1591f646eaa5cf892613f2c0f9
Source dataset
uspto-grants-2010_03
Patent number
US07671063B2

Reaction notes

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