3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzoyl chloride → HCID 66883374, compound

HRID 2242072Notes

Reaction equation

HRID 2242072 reaction equation
[CH:1]1([CH2:4][O:5][C:6]2[CH:7]=[C:8]([CH:12]=[CH:13][C:14]=2[O:15][CH:16]([F:18])[F:17])[C:9](Cl)=[O:10])[CH2:3][CH2:2]1.[Cl:19][C:20]1[CH:21]=[N:22][CH:23]=[C:24]([Cl:39])[C:25]=1[CH2:26][C:27]([C:29]1[CH:34]=[CH:33][C:32]([O:35][CH3:36])=[C:31]([O:37][CH3:38])[CH:30]=1)=[O:28]>>[Cl:39][C:24]1[CH:23]=[N:22][CH:21]=[C:20]([Cl:19])[C:25]=1/[CH:26]=[C:27](\[O:28][C:9](=[O:10])[C:8]1[CH:12]=[CH:13][C:14]([O:15][CH:16]([F:18])[F:17])=[C:6]([O:5][CH2:4][CH:1]2[CH2:2][CH2:3]2)[CH:7]=1)/[C:29]1[CH:34]=[CH:33][C:32]([O:35][CH3:36])=[C:31]([O:37][CH3:38])[CH:30]=1

Participants

3

Reactant 2

HCID 120473303-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzoyl chlorideHCID 668811982-(3,5-Dichloro-pyridin-4-yl)-1-(3,4-dimethoxy-phenyl)-ethanone

Product 1

HCID 66883374HCID 66883374, compound

Procedure

The compound was obtained starting from 3-cyclopropylmethoxy-4-difluoromethoxy -benzoyl chloride and 2-(3,5-dichloro-pyridin-4-yl)-1-(3,4-dimethoxy -phenyl)-ethanone, following the procedure of Example 7.

Workup

  1. customThe compound was obtained

Sources & evidence

ORD record
ord-5db2f70aa22d4d9f837ca7b9ad5c2f90
Source dataset
uspto-grants-2010_03
Patent number
US07671066B2

Reaction notes

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