HCID 68687267, compound → HCID 11671864, compound

HRID 2242083Notes

Reaction equation

[CH2:1]([O:3][C:4]1[C:27]([O:28][CH3:29])=[CH:26][C:7]2[C:8]([C:17]3[CH:25]=[CH:24][C:20]([C:21]([OH:23])=O)=[CH:19][CH:18]=3)=[N:9][C@H:10]3[C@@H:15]([C:6]=2[CH:5]=1)[CH2:14][N:13]([CH3:16])[CH2:12][CH2:11]3)[CH3:2].[CH3:30][O:31][C:32]1[CH:33]=[C:34]([CH:44]=[C:45]([O:47][CH3:48])[CH:46]=1)[CH2:35][O:36][CH2:37][C@@H:38]([NH:40][CH:41]([CH3:43])[CH3:42])[CH3:39]>>[CH3:48][O:47][C:45]1[CH:44]=[C:34]([CH:33]=[C:32]([O:31][CH3:30])[CH:46]=1)[CH2:35][O:36][CH2:37][C@@H:38]([N:40]([CH:41]([CH3:43])[CH3:42])[C:21](=[O:23])[C:20]1[CH:24]=[CH:25][C:17]([C:8]2[C:7]3[CH:26]=[C:27]([O:28][CH3:29])[C:4]([O:3][CH2:1][CH3:2])=[CH:5][C:6]=3[C@@H:15]3[C@@H:10]([CH2:11][CH2:12][N:13]([CH3:16])[CH2:14]3)[N:9]=2)=[CH:18][CH:19]=1)[CH3:39]

Participants

Reactant 2

HCID 68687267HCID 68687267, compound

HCID 68688601HCID 68688601, compound

Product 1

HCID 11671864HCID 11671864, compound

Procedure

Prepared from 4-((4aR,10bS)-9-ethoxy-8-methoxy-2-methyl-1,2,3,4,4a,10b-hexahydro-benzo[c][1,6]naphthyridin-6-yl)benzoic acid and [(S)-2-(3,5-dimethoxy-benzyloxy)-1-methyl-ethyl]-isopropyl-amine as described for example 1.

Sources & evidence

ORD record: ord-58856f6deb734605bc0d6eff2076994c
Source dataset: uspto-grants-2010_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07671068B2

Reaction notes

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