HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → (4-bromopyridin-3-yl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 4-Bromopyridine-3-carbaldehyde | HCID 11116740 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | (4-bromopyridin-3-yl)methanol | HCID 435086 | — |
Reaction Steps
4-Bromo-pyridine-3-carbaldehyde (240 mg) in ethanol (10 mL) at 0° C. was treated with sodium borohydride (139 mg) for 30 min. The reaction mixture was then diluted with ethyl acetate and washed with aqueous ammonium chloride and brine to yield (4-bromo-pyridin-3-yl)-methanol as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07671065B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-aef0f07cc03049b89750b81fd72b0811 |
| Source note | uspto-grants-2010_03 |