{5-[5-(4-Isobutylphenyl)-1,2,4-oxadiazol-3-yl]pyrazin-2-yl}methanol → HCID 59204300, compound

HRID 2242226Notes

Reaction equation

HRID 2242226 reaction equation
[CH2:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[O:15][N:14]=[C:13]([C:16]3[N:17]=[CH:18][C:19]([CH2:22][OH:23])=[N:20][CH:21]=3)[N:12]=2)=[CH:7][CH:6]=1)[CH:2]([CH3:4])[CH3:3].C(C1C=CC(C2N=C(C3C=CC(C=O)=NC=3)ON=2)=CC=1)C(C)C>>[CH2:1]([C:5]1[CH:6]=[CH:7][C:8]([C:11]2[O:15][N:14]=[C:13]([C:16]3[N:17]=[CH:18][C:19]([CH:22]=[O:23])=[N:20][CH:21]=3)[N:12]=2)=[CH:9][CH:10]=1)[CH:2]([CH3:4])[CH3:3]

Participants

3

Reactant 2

HCID 59204266{5-[5-(4-Isobutylphenyl)-1,2,4-oxadiazol-3-yl]pyrazin-2-yl}methanolHCID 592042795-[3-(4-Isobutyl-phenyl)-[1,2,4]oxadiazol-5-yl]-pyridine-2-carbaldehyde2×

Product 1

HCID 59204300HCID 59204300, compound

Procedure

The title compound was prepared from {5-[5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl]pyrazin-2-yl}methanol by procedures analogous to those described in Preparation 4F for the preparation of 5-[3-(4-isobutyl-phenyl)-[1,2,4]oxadiazol-5-yl]-pyridine-2-carbaldehyde.

Sources & evidence

ORD record
ord-382cea3f2f5e4796b5197c83dd001a34
Source dataset
uspto-grants-2010_03
Patent number
US07671043B2

Reaction notes

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