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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2242265Generated: October 31, 2026

HCID 66781693, compound → HCID 66782507, compound

https://huagongshe.com/reaction/2242265

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66781693HCID 66781693—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 66782507HCID 66782507—

Reaction Steps

To a solution of [1-[Benzyl-(2,2-diethoxy-ethyl)-carbamoyl]-2-(4-tert-butoxy-phenyl)-ethyl]-carbamic acid benzyl ester (3.32 g, 5.76 mmol) in MeOH (50 mL) was added Pd/C (500 mg). After 2 h of stirring under H2 atmosphere, the solution was filtered on Celite and the solvent was evaporated to afford 2-Amino-N-benzyl-3-(4-tert-butoxy-phenyl)-N-(2,2-diethoxy-ethyl)-propionamide, which was used next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07671054B1
Source datasetuspto-grants-2010_03
ORD IDord-cae79eb71fee4bba979c5f80f2f6de5f
Source noteuspto-grants-2010_03