HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Methioninol → 5-Cyano-1-(3-trifluoromethoxybenzyl)-1H-indole-2-carboxylic acid (1-hydroxymethyl-3-methylsulfanylpropyl)amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Methioninol | HCID 2724404 | — |
| Reactant | 5-cyano-1-(3-trifluoromethoxybenzyl)-1H-indole-2-carboxylic acid | HCID 68543106 | — |
| Product | 5-Cyano-1-(3-trifluoromethoxybenzyl)-1H-indole-2-carboxylic acid (1-hydroxymethyl-3-methylsulfanylpropyl)amide | HCID 59205430 | — |
Reaction Steps
The title compound was prepared using 5-cyano-1-(3-trifluoromethoxybenzyl)-1H-indole-2-carboxylic acid [prepared from 3-(trifluoromethoxy)benzyl bromide and ethyl 5-cyanoindole-2-carboxylate] and L-(−)-methioninol in a manner similar to that described in Example 11.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07671080B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-06ef71ce05c64bde813de78aa357e383 |
| Source note | uspto-grants-2010_03 |