HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminothiophenol → 2-(2-Aminophenyl)sulfanylbenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminothiophenol | HCID 8713 | — |
| Reactant | 2-Fluorobenzonitrile | HCID 67855 | — |
| Reactant | Dibenzothiazepine | HCID 66579101 | — |
| Product | 2-(2-Aminophenyl)sulfanylbenzonitrile | HCID 366233 | — |
Reaction Steps
WO 92/19607 reports that a dibenzothiazepine derivative can be prepared by the steps of reacting 2-amino-thiophenol with 2-fluorobenzonitrile to give 2-(2-amino-phenylthio)benzonitrile, hydrolyzing the resultant compound to give 2-(2-carboxyphenylthio)aniline, and finally cyclizing the aniline derivative.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07671195B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-d98936e8f53946449a120941803de46e |
| Source note | uspto-grants-2010_03 |