Methanol → HCID 59205325, compound

Participants

Reaction Steps

To a solution of the material prepared in Step B (3.0 g, 6.1 mmol) in THF (30 mL) was added methanol (10 mL) followed by 1N aqueous lithium hydroxide (30 mL). After 24 h at ambient temperature the mixture was brought to pH 1 with 1N aqueous sodium bisulfate. The mixture was extracted with 100 mL of ethyl acetate. The organic layer was washed with brine, dried (magnesium sulfate), and concentrated in vacuo, affording the title compound. This was used without further purification. LC/MS 406.2 (M+1).

Provenance & Evidence