反应详情

60.5 g (0.226 mol) of N-3-pentylidene-(3-phenoxybenzylamine is dissolved in 50 ml of toluene; to the solution is then added 2 g (0.0179 mol) of potassium tert-butylate, and the mixture is refluxed for 4 hours. After cooling of the reaction mixture, extraction is effected by shaking with 50 ml of water, and the organic phase is separated in a separating funnel. The toluene is distilled off in a slight water-jet vacuum to leave 56 g (0.21 mol) of 3-phenoxybenzylidene-3-pentylamine, corresponding to a yield of 92.5% of theory; b.p. 125° C./Pa.

1. temperaturethe mixture is refluxed for 4 hours
2. temperatureAfter cooling of the reaction mixture, extraction
3. customthe organic phase is separated in a separating funnel
4. distillationThe toluene is distilled off in a slight water-jet vacuum