反应详情

温度

110 °C

To a mixture of 4-bromopyridin-2-amine (2 g, 11.56 mmol) in chloroform (10 mL), isocyanatoethane (0.913 mL, 11.56 mmol) was added, and the resulting reaction mixture was heated at 110° C. for 2 h. The reaction mixture was concentrated under reduced pressure and triturated with acetonitrile, then collected by filtered to give the title compound as a white solid (2.15 g).

1. additionwas added
2. customthe resulting reaction mixture
3. concentrationThe reaction mixture was concentrated under reduced pressure
4. customtriturated with acetonitrile
5. customcollected
6. filtrationby filtered