HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzoic Acid → 2-(4-Chlorophenyl)-5-nitrobenzimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzoic Acid | HCID 6318 | — |
| Reactant | 4-Nitro-1,2-phenylenediamine | HCID 5111791 | — |
| Solvent | Toluene ethylacetate | HCID 21584019 | — |
| Product | 2-(4-Chlorophenyl)-5-nitrobenzimidazole | HCID 376353 | 87% |
Reaction Steps
Prepared from 4-chlorobenzoic acid (17.83 g, 0.114 mol) and 2-amino-5-nitroaniline (18 g, 0.114 mol), in a manner similar to that of Example 9b. Yield: 87%; Rf (6/4 toluene/ethyl acetate): 0.61; m.p.: 302.5-305° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07674809B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-485e980b42c54534940b73b1b748e46c |
| Source note | uspto-grants-2010_03 |