HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzenesulfonyl chloride → 4-Chloro-N-{2-ethyl-1-[1-(4-methoxybenzyl)-1H-pyrazol-5-yl]butyl}benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzenesulfonyl chloride | HCID 7398 | — |
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | {2-ethyl-1-[1-(4-methoxybenzyl)-1H-pyrazol-5-yl]butyl}amine | HCID 68593849 | — |
| Product | 4-Chloro-N-{2-ethyl-1-[1-(4-methoxybenzyl)-1H-pyrazol-5-yl]butyl}benzenesulfonamide | HCID 11431146 | 52% |
Reaction Steps
The compound of example 2 was synthesized from {2-ethyl-1-[1-(4-methoxybenzyl)-1H-pyrazol-5-yl]butyl} amine in a manner similar to that of example 1 but using 4-chlorobenzenesulfonyl chloride as the sulfonyl chloride in step 1D. The product was isolated as white foam in 52% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07674813B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-f89f79a4e4ce4373b478e53b2922e6e7 |
| Source note | uspto-grants-2010_03 |