HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl (7E)-8-{2-[(4-cyclohexylbenzyl)oxy]phenyl}-6-oxo-7-octenoate → Methyl 8-{2-[(4-cyclohexylbenzyl)oxy]phenyl}-6-oxooctanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl (7E)-8-{2-[(4-cyclohexylbenzyl)oxy]phenyl}-6-oxo-7-octenoate | HCID 59210853 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Methyl 8-{2-[(4-cyclohexylbenzyl)oxy]phenyl}-6-oxooctanoate | HCID 59210668 | — |
Reaction Steps
A suspension of 2.80 g (6.44 mmol) of methyl (7E)-8-{2-[(4-cyclohexylbenzyl)-oxy]phenyl}-6-oxo-7-octenoate XIII and 0.06 g of Pd/C (10% Pd) in 30 ml of ethyl acetate was stirred under an atmosphere of hydrogen for 3 h. The catalyst was removed by filtration through Celite, and the product was purified chromatographically (silica gel, cyclohexane/ethyl acetate 20:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07674825B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-43abae2605a64014a979ea4f6756e320 |
| Source note | uspto-grants-2010_03 |