HCID 137227827, compound → HCID 131727936, compound

Participants

Reaction Steps

Carry out the procedure as in Example 6, starting from 1.57 g of 4-(1H-benzimidazol-2-yl)-fluoren-9-one oxime (Z,E), obtained in Example 68, and 5.6 mg of Raney Nickel in 80 ml of ethanol and 80 ml of tetrahydrofuran for 4 hours at 60° C. under a hydrogen pressure of 1 bar. After purification by making a paste in diisopropyl ether, we obtain 1.31 g of 4-(1H-benzimidazol-2-yl)-9H-fluoren-9(R,S)-ylamine, in the form of a white powder, with the following characteristics:

Provenance & Evidence