HCID 178526304, compound → HCID 178507132, compound

Participants

Reaction Steps

Carry out the procedure as in Example 6, starting from 1.30 g of 4-(3H-imidazo[4,5-b]pyridin-2-yl)-9H-fluoren-9-one oxime (Z,E), obtained in the preceding stage, and 2.45 mg of Raney Nickel in 65 ml of ethanol and 65 ml of tetrahydrofuran for 5 hours at 60° C. under a hydrogen pressure of 1 bar. After purification by making a paste in diisopropyl ether, we obtain 1.06 g of 4-(3H-imidazo[4,5-b]pyridin-2-yl)-9H-fluoren-9(R,S)-ylamine, in the form of a white powder, with the following characteristics:

Provenance & Evidence