HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 309690, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 3-Aminophenol | HCID 11568 | — |
| Reactant | HCID 59211314 | HCID 59211314 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 309690 | HCID 309690 | — |
Reaction Steps
Pyridine (14 g, 0.18 Mol) and 4-nitrophenylacetic acid (32 g, 0.18 Mol) were stirred in toluene (100 ml) whilst trimethylacetylchloride (21 g, 0.18 Mol) was added. The toluene was evaporated to yield 4-nitrophenylacetic-trimethylacetic anhydride. 3-Aminophenol (20 g, 0.18 Mol) was stirred in DMF (100 ml) and treated with the mixed anhydride and pyridine (14 g) in dimethylformamide (DMF) dropwise. The solution was diluted with water and the product isolated by filtration and dried (19 g, 39%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07674918B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-d8baceefeae44bc0af7244b02c775841 |
| Source note | uspto-grants-2010_03 |