HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 7-Methoxy-1-oxo-1H-pyrimido[6,1-b]benzthiazole-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-(2-Mercapto-4-methoxyphenyl)-5-carboxypyrimidine-2,6-dione | HCID 23332805 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 7-Methoxy-1-oxo-1H-pyrimido[6,1-b]benzthiazole-4-carboxylic acid | HCID 23332789 | — |
Reaction Steps
29.4 g. 1-(2-Mercapto-4-methoxyphenyl)-5-carboxypyrimidine-2,6-dione are boiled for 6 hours in 300 ml. of a semi-concentrated dioxane solution of hydrochloric acid. The 7-methoxy-1-oxo-1H-pyrimido[6,1-b]benzthiazole-4-carboxylic acid which is thereby formed can be obtained in practically quantitative yield by suction filtration of the hot solution. The physical data of the product agree with those of the compound prepared according to Variant I.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04232024 |
| Source dataset | uspto-grants-1980_11 |
| ORD ID | ord-5daf0a5af2364bbb963622d9cb02d2df |
| Source note | uspto-grants-1980_11 |