HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbamate → HCID 68544451, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbamate | HCID 276 | — |
| Reactant | Methyl chloroformate | HCID 6586 | — |
| Reactant | HCID 68548829 | HCID 68548829 | — |
| Product | HCID 68544451 | HCID 68544451 | 63.7% |
Reaction Steps
Step B Carbamate Formation: Addition of methyl chloroformate (0.05 mL, 0.65 mmol) to 7-(Cyclohexylmethyl-amino)-1-ethoxycarbonylmethoxy-3,8-dithia-cyclopenta[a]indene-2-carboxylic acid methyl ester (60 mg, 0.13 mmol) was carried out following a procedure similar to that delineated in Step B, Example 27, affording 43 mg of 7-(Cyclohexylmethyl-methoxycarbonyl-amino)-1-ethoxycarbonylmethoxy-3,8-dithia-cyclopenta[a]indene-2-carboxylic acid methyl ester (63% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07674822B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-320d43a5502347358a529446d2117617 |
| Source note | uspto-grants-2010_03 |