HCID 68547768, compound → HCID 11511505, compound

Participants

Reaction Steps

Step C Hydrolysis: Hydrolysis of 7-(1-Cyclohexylmethyl-3-ethyl-ureido)-1-ethoxycarbonylmethoxy-3,8-dithia-cyclopenta[a]indene-2-carboxylic acid methyl ester (30 mg, 0.056 mmol) was carried out following a procedure similar to that delineated in Step C, Example 26, with the exception of an ethyl acetate wash (3×, 5 mL) before precipitation of the desired diacid, to remove a minor impurity associated with the isocyanate. (8.6 mg yellow solid, 28% yield).

Provenance & Evidence