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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2243529Generated: November 1, 2026

Benzyl [2-isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]acetate → [2-Isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]acetic acid

https://huagongshe.com/reaction/2243529

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl [2-isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]acetateHCID 86605504—
CatalystHCID 178418390HCID 178418390—
SolventEthanolHCID 702—
Product[2-Isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]acetic acidHCID 2313428283.3%

Reaction Steps

A mixture of benzyl [2-isopropyl-4-(4,4,5,5-tetramethyl -1,3,2-dioxaborolan-2-yl)phenoxy]acetate (0.24 g) and 10% palladium-carbon (0.05 g) in ethanol (10 mL) was stirred at room temperature for 2 hrs under an atmosphere of hydrogen. The catalyst was removed by filtration, and the solvent was evaporated under reduced pressure to afford the title compound (0.156 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07674938B2
Source datasetuspto-grants-2010_03
ORD IDord-1c501995b4324ab9b6f54abffc4cf86a
Source noteuspto-grants-2010_03