HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2243591Generated: October 31, 2026
N-Iodosuccinimide → HCID 178516673, compound
https://huagongshe.com/reaction/2243591
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N-Iodosuccinimide | HCID 120273 | — |
| Reactant | 5-Fluoro-4-methoxymethoxy-3-phenyl-2-(triethylsilanyl)-furo[2,3-b]pyridine | HCID 58608098 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178516673 | HCID 178516673 | — |
Reaction Steps
The mixture of 5-fluoro-4-methoxymethoxy-3-phenyl-2-(triethylsilanyl)-furo[2,3-b]pyridine (4) (0.10 g, 0.26 mmol) and NIS (0.07 g, 0.31 mmol) in DMF (1.5 mL) was stirred at 50° C. overnight. The reaction mixture was purified by preparative HPLC to give the title compound 5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07674907B2 |
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| Source dataset | uspto-grants-2010_03 |
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| ORD ID | ord-01b8c8c96dcd4f6cb8dd99f87537f75c |
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| Source note | uspto-grants-2010_03 |
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