HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoroaniline → 3-[(4-Fluorophenylimino)methyl]benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoroaniline | HCID 9731 | — |
| Reactant | m-Formylbenzonitrile | HCID 90670 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 3-[(4-Fluorophenylimino)methyl]benzonitrile | HCID 22252051 | — |
Reaction Steps
88 ml of para-fluoroaniline are added dropwise to 12 g of meta-cyanobenzaldehyde in 60 ml of isopropanol. After 1 h at 60° C., the product precipitates out. The mixture is allowed to warm to room temperature and filtered off, and the residue is washed with isopropanol. Drying gives 11 of m.p. 101° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07674773B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-fd5d9a5a514f407e9acbfac8a3cbc4f6 |
| Source note | uspto-grants-2010_03 |