N-[4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3-thiophenecarboxamide → HCID 11949929, compound

Participants

Role	Name	HCID	Charge
Reactant	N-[4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3-thiophenecarboxamide	HCID 21914662	—
Reactant	5-Chloro-1-(2,6-difluorophenyl)-7-(methylthio)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one	HCID 57530500	—
Product	HCID 11949929	HCID 11949929	—

Reaction Steps

The title compound was prepared from 5-Chloro-1-(2,6-difluorophenyl)-7-(methylthio)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one by following the procedures in Example 1d except using N-[4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3-thiophenecarboxamide for the Suzuki cross-coupling reaction. LC-MS m/z 524 (M+H)+, 2.21 min (ret. time). xdb

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07674789B2
Source dataset	uspto-grants-2010_03
ORD ID	ord-7f98b64dc70a46489381f420a8786ff2
Source note	uspto-grants-2010_03