Trifluoroacetic acid → HCID 23081132, compound

Participants

Reaction Steps

4-[4-(2-Methyl-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazol-2-ylmethoxy)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester is treated with trifluoroacetic acid (5 ml) and stirred at room temperature for 1 hr. The mixture is concentrated and 2-methyl-6-nitro-2-(4-piperazin-1-yl-phenoxymethyl)-2,3-dihydro-imidazo[2,1-b]oxazole is isolated as a dark oil and used for subsequent step without further purification.

Provenance & Evidence