Hydrazine hydrate (1:1) → 1-Methyl-2-oxo-1,2-dihydropyridine-4-carbohydrazide

Participants

Reaction Conditions

Reaction Steps

The title compound of example 24 (4.0 g, 23.9 mmol) was dissolved in ethanol (50 mL). Hydrazine hydrate (5.8 mL, 119 mmol) was added and the reaction was stirred at 78° C. for 3 hours. The reaction mixture was then cooled to room temperature and the product was filtered off to give 3.13 g (78% yield) of the title compound as a light yellow solid.

Provenance & Evidence