反应详情

A mixture of 6-amino-2,4-bis(trichloromethyl)benzo[1,3]dioxin (1.0 g.), acetyl chloride (1 ml.) and acetic anhydride (25 ml.) was warmed on a steam bath for 5 hours. The reaction mixture was cooled and evaporated to dryness under reduced pressure. Trituration of the oily residue with aqueous ethanol gave a solid product, which was crystallised from ethanol to give 6-diacetylamino-2,4-bis(trichloromethyl)benzo[1,3]dioxin, m.p. 147°-148° C.

1. temperaturewas warmed on a steam bath for 5 hours
2. temperatureThe reaction mixture was cooled
3. customevaporated to dryness under reduced pressure
4. customTrituration of the oily residue with aqueous ethanol gave a solid product, which
5. customwas crystallised from ethanol