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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2243940Generated: November 1, 2026

Hydrazine hydrate (1:1) → 3-(4-Fluoro-2-methylphenyl)-5,6,7,8-tetrahydro-5,8-methanocinnoline

https://huagongshe.com/reaction/2243940

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrazine hydrate (1:1)HCID 24654—
ReactantBicyclo(2.2.1)heptane-2,3-dioneHCID 138696—
ReactantHCID 86609925HCID 86609925—
Product3-(4-Fluoro-2-methylphenyl)-5,6,7,8-tetrahydro-5,8-methanocinnolineHCID 67363372—

Reaction Steps

yellow oil. MS (EI): 254.2 (M+). Prepared from bicyclo[2.2.1]heptane-2,3-dione, [2-(4-Fluoro-2-methyl-phenyl)-2-oxo-ethyl]-phosphonic acid dimethyl ester, hydrazine monohydrate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07678795B2
Source datasetuspto-grants-2010_03
ORD IDord-d51f218bfe5746e3a2dba08db20049dd
Source noteuspto-grants-2010_03