Potassium Carbonate → HCID 43333337, compound

Participants

Reaction Steps

Add 4-aminobenzonitrile (3.125 g, 26.4 mmol) and potassium carbonate (8.04 g, 58.2 mmol) to a solution of 4-chloromethyl-benzoyl chloride (5.00 g, 26.4 mmol) in acetone (60 mL). Heat at reflux for 4 hours. Cool to room temperature, filter, and concentrate to afford the title compound as a yellow solid (7.30 g, 91%): 1H NMR (DMSO-d6) δ 4.86 (s, 2H), 7.61 (d, 2H), 7.83 (d, 2H), 7.94-8.03 (m, 4H), 10.72 (s, 1H).

Provenance & Evidence