HCID 11555215, compound → HCID 23677045, compound

Participants

Reaction Steps

Stir 3-[4-(4-acetyl-3-hydroxy-2-propyl-phenoxymethyl)-benzenesulfonylamino]-benzoic acid (200 mg, 0.41 mmol) in ethyl acetate (10 mL) as a suspension. Add sodium 2-ethylhexanoate (92 mg, 0.90 mmol) in ethyl acetate (1 mL). After 12 hours at ambient temperature, concentrate the mixture under reduced pressure, sonicate the residue with ether (10 mL) and collect the title compound by filtration as a white solid (191 mg, 0.41 mmol): 1H NMR (DMSO-d6) δ 0.85 (t, 3H), 1.48 (m, 2H), 2.58 (m, 5H), 5.30 (s, 2H), 6.62 (d, 1H), 7.08 (m, 2H), 7.40 (m, 1H), 7.53 (m, 3H), 7.78 (m, 3H), 12.82 (s, 1H); MS (m/z): 482. (M−1).

Provenance & Evidence