HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzoic Acid → Ethyl 3-(4-Fluorophenyl)-3-Oxopropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzoic Acid | HCID 9973 | — |
| Reactant | 2,2-Dimethyl-1,3-dioxane-4,6-dione | HCID 16249 | — |
| Reactant | Ethyl 3-oxo-3-(thiophen-2-yl)propanoate | HCID 255159 | — |
| Reactant | 4-(Thiophen-2-yl)pyrimidin-2-amine | HCID 2764407 | — |
| Product | Ethyl 3-(4-Fluorophenyl)-3-Oxopropanoate | HCID 2758844 | — |
Reaction Steps
This material is prepared by a method analogous to that described for preparation of ethyl 3-oxo-3-(2-thienyl)propanoate in preparation of 1D, starting from 2,2-dimethyl-1,3-dioxane-4,6-dione and 4-fluorobenzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07678804B2 |
| Source dataset | uspto-grants-2010_03 |
| ORD ID | ord-9bf52d83612144739785fa8630a0b389 |
| Source note | uspto-grants-2010_03 |