HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuryl chloride → 3-Bromo-5-chloro-2,6-dimethoxybenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | 3-Bromo-2,6-dimethoxybenzoic acid | HCID 2774744 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 3-Bromo-5-chloro-2,6-dimethoxybenzoic acid | HCID 2800463 | — |
Reaction Steps
A solution of 40 ml (0.5 mol) of sulphuryl chloride in 100 ml of chloroform is added dropwise to a solution of 26.1 g (0.1 mol) of 3-bromo-2,6-dimethoxybenzoic acid in 150 ml of chloroform. After a night at room temperature the solution is refluxed for 45 minutes. The solvent is evaporated and the residue recrystallized from isopropyl ether - light petroleum. Yield: 23.5 g, m.p. 98.5°-100° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04232037 |
| Source dataset | uspto-grants-1980_11 |
| ORD ID | ord-a0df755bb7b74005aa58054f65e99638 |
| Source note | uspto-grants-1980_11 |