4-Bromopyridine → HCID 11617146, compound

HRID 2244409Notes

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]([C:11]2[N:12]=[C:13]([CH3:17])[S:14][C:15]=2[NH2:16])=[O:10])[CH:5]=[CH:6][CH:7]=1.Br[C:19]1[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:8][C:9]([C:11]2[N:12]=[C:13]([CH3:17])[S:14][C:15]=2[NH:16][C:19]2[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=2)=[O:10])[CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 142684-Bromopyridine

HCID 11608689HCID 11608689, compound

Product 1

HCID 11617146HCID 11617146, compound

Procedure

The title compound was prepared by reaction of 5-amino-2-methyl-thiazole-4-carboxylic acid (3-chloro-phenyl)-amide (prepared as illustrated in example 127) with 4-bromopyridine, as follows.

Sources & evidence

ORD record: ord-9e2d2bd779fb436c9beb71b8be6053c6
Source dataset: uspto-grants-2010_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07678815B2

Reaction notes

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