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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2244697Generated: October 30, 2026

Pyrrolidine → HCID 72437167, compound

https://huagongshe.com/reaction/2244697

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
ReactantHCID 72437164HCID 72437164—
ProductHCID 72437167HCID 72437167—

Reaction Steps

In analogy to example 24B 5-chloro-thiophene-2-carboxylic acid {(1RS,4SR)-4-[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-2-oxo-cyclopentylmethyl}-amide was reacted with pyrrolidine to give 5-chloro-thiophene-2-carboxylic acid {(1RS,4SR)-4-[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-2-pyrrolidin-1-yl-cyclopentylmethyl}-amide. Off-white crystalline solid. 543.3 ([M+H]+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07678917B2
Source datasetuspto-grants-2010_03
ORD IDord-d7d455d3ebf3478e9b9388b922cffc67
Source noteuspto-grants-2010_03