Methylamine → HCID 58826475, compound

Participants

Reaction Steps

In analogy to example 25 5-chloro-thiophene-2-carboxylic acid {(1RS,4SR)-4-[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-2-oxo-cyclopentylmethyl}-amide (example 32A) was reacted with methylamine (solution in THF) to give 5-chloro-thiophene-2-carboxylic acid {4-[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-2-methylamino-cyclopentylmethyl}-amide. Light yellow solid. 503.3 ([M+H]+).

Provenance & Evidence