1-(Propan-2-yl)piperidin-4-amine → N-(1-isopropylpiperidin-4-yl)-2-(2-methylphenyl)-2-(4-chlorophenylamino-carbonylamino)-acetamide
반응식
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]([NH:12][C:13]([NH:15][C:16]1[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=1)=[O:14])[C:9]([OH:11])=O.[CH:23]([N:26]1[CH2:31][CH2:30][CH:29]([NH2:32])[CH2:28][CH2:27]1)([CH3:25])[CH3:24]>>[CH:23]([N:26]1[CH2:31][CH2:30][CH:29]([NH:32][C:9](=[O:11])[CH:8]([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[CH3:1])[NH:12][C:13]([NH:15][C:16]2[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=2)=[O:14])[CH2:28][CH2:27]1)([CH3:25])[CH3:24]참가 물질
3
실험 절차
The titled compound was prepared analogously as describe in EXAMPLE 82, using 2-(2-methylphenyl)-2-(4-chlorophenylaminocarbonylamino)-acetic acid and 1-isopropyl-4-aminopiperidine. MS 443.2 and 445.2 (M+H, Cl pattern).
출처 및 근거
- ORD 기록
- ord-95052435ab7f4545874a9c40c520def6
- 출처 데이터셋
- uspto-grants-2010_03
- 특허 번호
- US07678913B2
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