1-(Propan-2-yl)piperidin-4-amine → HCID 11619601, compound

HRID 2244999Notes

Reaction equation

HRID 2244999 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]([NH:12][C:13]([NH:15][C:16]1[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=1)=[O:14])[C:9]([OH:11])=O.[CH:23]([N:26]1[CH2:31][CH2:30][CH:29]([NH2:32])[CH2:28][CH2:27]1)([CH3:25])[CH3:24]>>[CH:23]([N:26]1[CH2:31][CH2:30][CH:29]([NH:32][C:9](=[O:11])[CH:8]([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[Cl:1])[NH:12][C:13]([NH:15][C:16]2[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=2)=[O:14])[CH2:28][CH2:27]1)([CH3:25])[CH3:24]

Participants

3

Reactant 2

HCID 31633331-(Propan-2-yl)piperidin-4-amineHCID 68692598HCID 68692598, compound

Product 1

HCID 11619601HCID 11619601, compound

Procedure

The titled compound was prepared analogously as describe in Example 82, using 2-(2-chlorophenyl)-2-(4-chlorophenylaminocarbonylamino)-acetic acid and 1-isopropyl-4-aminopiperidine. MS 463.1, 464.1, 465.1 and 466.1 (M+H, 2Cl pattern).

Sources & evidence

ORD record
ord-bd73c4f2d5654561b01d8a26c74b9bb7
Source dataset
uspto-grants-2010_03
Patent number
US07678913B2

Reaction notes

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